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Alcohol and Its Impact on the Gut & Overall Health

Alcohol and Its Impact on the Gut & Overall Health

Alcohol is a common part of social life, relaxation, and celebration. But its effects on your health, particularly on your gut and overall well-being, are worth a closer look.

The COVID-19 pandemic revealed some interesting insights into alcohol consumption trends, both in the U.S. and globally. A survey from Johns Hopkins and the University of Maryland-Baltimore found that 60.1% of participants reported drinking more alcohol after March 1, 2020, with 45.7% attributing this increase to heightened stress.

At the same time, memes and reels were circulating, joking about the rise in alcohol use. Yet, 24% of adults reported binge drinking in the last 30 days. These trends reflect how stress and uncertainty influenced drinking habits during this time.

My aim here isn’t to say “never drink” but to provide facts so you can make informed choices that align with your health goals. We’ll explore how alcohol can influence everything from your liver to your gut and why certain risks might be more significant than we once thought.

No Amount of Alcohol is Safe - The Evidence

While moderate drinking may seem harmless, new research highlights that even small amounts carry risks. A 2023 statement from the World Health Organization (WHO), confirms that alcohol contributes to numerous health risks, and no level of consumption is without harm.

Let’s dive into some of the key research findings around alcohol and its effects on our health.

Alcohol is a Class 1 Carcinogen

Let’s start with one of the most serious risks associated with alcohol: its classification as a Class 1 carcinogen. This puts alcohol in the same category as tobacco and asbestos as a cancer-causing substance.

According to the International Agency for Research on Cancer (IARC), alcohol is known to cause cancer in humans. This includes cancers of the mouth, throat, liver, and breast. Even moderate consumption carries a risk, making alcohol one of the most dangerous substances many people regularly consume.

Alcohol’s Impact on Key Health Outcomes

Alcohol’s effects extend far beyond cancer risk. Even in small amounts, alcohol consumption increases the risk of osteoporosis, stroke, gum disease, and liver cirrhosis. What’s important to note is that these risks are dose-dependent, meaning that as alcohol consumption increases, so does the body burden (allostatic load) and likelihood of developing associated health conditions.

Studies also link alcohol use to poor mental health outcomes, cognitive decline, and neurodegenerative diseases like Alzheimer’s, highlighting how far-reaching the effects of alcohol can be on overall health.

Disputing the “Moderate Drinking” Myth

For years, the idea of moderate drinking—particularly red wine—being beneficial to health has persisted, largely due to the "French paradox." This idea and several studies suggested red wine could protect against heart disease and kidney disease. 

However, while these findings garnered attention, newer research emphasizes that alcohol’s toxic effects on other organs—like the liver and brain—outweigh any potential benefits.

It’s important to recognize that while some studies, especially randomized controlled trials (RCTs), suggest that moderate drinking may benefit heart health, they often focus on isolated outcomes. But our organs don’t operate in isolation.

By comparing specific variables, such as alcohol’s effect on heart health alone, these studies can miss the broader, more concerning picture: alcohol is still a known carcinogen. This is something to keep in mind whenever you read a research headline.

In functional medicine, we emphasize a holistic approach, recognizing that health involves the whole body, not just individual parts. What benefits one area might harm another. It’s about balance and understanding beyond the headlines!

Alcohol’s Impact on Gut Health

Alcohol is absorbed in the stomach and small intestine. It affects the gut environment in profound ways, contributing to inflammation, disrupting the microbiome, and compromising nutrient absorption, all of which can have long-term consequences for overall health.

Alcohol and Gut Inflammation

Studies indicate that alcohol consumption elevates levels of toxins, like lipopolysaccharides (LPS), in the gut for days after drinking. LPS, a toxic substance produced by certain gut bacteria, can drive inflammation and compromise gut health, such as in increased intestinal permeability (leaky gut). 

Chronic inflammation from alcohol consumption can also exacerbate many diseases across the entire body, making its impact on gut health particularly concerning.

Alcohol’s Effects on the Microbiome

Your gut is home to trillions of bacteria, many of which are essential for maintaining overall health. Alcohol disrupts the balance of good and bad bacteria, leading to an imbalanced gut microbiome, a condition known as dysbiosis.

Alcohol has been shown to reduce levels of beneficial bacteria such as Lactobacillus and Bifidobacterium, which are important for digestion, immunity, and even mood regulation. This imbalance can lead to conditions like Small Intestinal Bacterial Overgrowth (SIBO) and candida overgrowth, both of which contribute to gut inflammation and further health complications. 

Studies have shown that alcohol alters the gut microbiome, reducing beneficial bacteria like Bacteroidetes and increasing harmful bacteria such as Proteobacteria, which are linked to inflammation and disease.

These changes in the gut microbiome not only impact digestion but also increase the presence of harmful LPS and create a pro-inflammatory environment! Overall, alcohol’s disruption of the gut microbiome contributes to systemic health problems ranging from Irritable Bowel Syndrome (IBS) to type II diabetes and cancers.

Alcohol Inhibiting Nutrient Absorption

Even with a nutrient-dense diet, alcohol interferes with your body’s ability to absorb essential vitamins and minerals. Research shows that alcohol affects the absorption of both macro and micronutrients, impairing the body’s ability to get what it needs for optimal function. When alcohol damages the gut lining, nutrient transporters in the small intestine become less effective.

Here are some of the key nutrients affected by alcohol consumption:

  • B Vitamins (especially B1, B2, B9, B12)—Essential for energy, brain function, and DNA synthesis, alcohol disrupts their absorption, increasing deficiency risks.
  • Vitamin C—An important antioxidant, while alcohol may increase its transporters and demand, its effectiveness doesn't improve, increasing potential oxidative stress.
  • Minerals (calcium, zinc, magnesium)—Alcohol disrupts the absorption of these critical minerals, contributing to issues like bone weakening and immune dysfunction.
  • Fat-soluble vitamins (A, D, E, and K)—Alcohol impairs their absorption, which can impact vision, bone health, immune response, and blood clotting.

Alcohol’s interference with these vital nutrients can leave you feeling fatigued, weak, and more prone to illness, particularly when alcohol consumption is chronic. The longer alcohol remains part of your routine, the greater the depletion of these nutrients, contributing to lasting health issues.

Cognitive Decline and the Gut-Brain Axis

The gut and brain are closely connected through the gut-brain axis, and what affects the gut influences mental and cognitive health. Alcohol disrupts this axis, leading to gut inflammation and microbiome imbalances that ultimately affect cognitive function, both short and long-term.

Gut bacteria play a role in producing neurotransmitters like GABA and serotonin, which influence mood and behavior. When alcohol-induced dysbiosis disrupts this production, it can contribute to mood issues like anxiety, memory problems, and neurotransmitter imbalances. 

Additionally, neurotransmitters are synthesized from the nutrients we consume and absorb, further impacted by alcohol. Over time, these disruptions may contribute to cognitive decline, further emphasizing the importance of a balanced gut microbiome for mental clarity and well-being.

How the Body Breaks Down Alcohol

When you drink alcohol, the liver converts it into acetaldehyde—a highly toxic compound linked to DNA damage, oxidative stress, and inflammation. Eventually, acetaldehyde is broken down further and eliminated, but this process requires resources such as antioxidants!

Glutathione is one of many crucial antioxidants that help detoxify acetaldehyde. Chronic drinking depletes glutathione, leaving the liver vulnerable to toxins, which heightens inflammation and the risk of liver damage.

Food for Thought: When you take painkillers, such as acetaminophen, after drinking from headache or handover, it further strains the liver’s already depleting glutathione levels. This can compound oxidative stress and potential damage.

Is Wine and Beer “Less Dangerous”?

Again, no amount of alcohol is considered healthy, but some studies show wine and beer may be “less harmful” than liquor. However, studies are mixed, and any alcohol carries risks, including inflammation, liver stress, and increased cancer risk.

Alcohol’s Effects on the 5 Lifestyle Pillars of Health

  • Movement & Exercise: Alcohol impairs muscle recovery, hydration, and motivation, all of which are vital for an active lifestyle. Over time, regular drinking can make it harder to stay fit and mobile.
  • Healing Nutrition: Alcohol depletes nutrients like B vitamins, zinc, and magnesium and increases cravings for processed foods, disrupting a balanced diet and microbiome.
  • Quality Sleep: Though alcohol may initially aid sleep, it disrupts restorative REM cycles, potentially leading to fatigue and weakened immunity over time.
  • Stress Management & Meditation: Alcohol temporarily numbs stress but raises cortisol, undermining long-term stress management and impairing mental clarity, especially in mindfulness practices.
  • Social Connection & Sense of Purpose: Alcohol can promote social bonding but may foster dependency and isolation. Long-term use often interferes with genuine connection and personal growth, especially in social settings centered around drinking.

Tips to Rethink and Reduce Alcohol Intake

If you're considering cutting back on alcohol, here are some simple, sustainable strategies:

  1. Gut-Friendly Alternatives—Enjoy nutrient-rich mocktails with gut-supporting ingredients like kombucha, ginger, and herbs for a satisfying alternative to alcohol.
  2. Boost Nutrient Intake—Alcohol depletes key nutrients like B vitamins and magnesium. To support your energy and overall health, add more nutrient-dense foods to your diet, such as leafy greens, nuts, and seeds. You might also consider a quality multivitamin like Cielo’s Rise.
  3. Prioritize Restorative Sleep—Consider starting by choosing alcohol-free evenings for deeper rest. Better sleep promotes recovery, stress resilience, and mental clarity.
  4. Explore Stress-Relief Alternatives—Swap out drinking for relaxation techniques like meditation, deep breathing, or journaling. These activities lower cortisol naturally and support long-term stress management without alcohol’s taxing effects.
  5. Reframe Social Connections—Seek out social activities that don’t center on drinking, like exercise classes or cooking nights. This reduces the likelihood of alcohol dependency in social situations and reinforces genuine connections.
  6. Set Clear Intentions—Define your goals regarding alcohol. Whether you plan to gradually reduce consumption or take breaks, setting intentions empowers you to make mindful choices that align with your health goals.

By focusing on small, positive changes, you can explore how reducing alcohol might benefit your energy, focus, and overall health.

Conclusion: Weighing the Risks of Alcohol

The research is clear: while alcohol may be an accepted part of social life, the potential risks far outweigh any perceived benefits. From disrupting gut health to increasing the risk of cancer and cognitive decline, alcohol's impact on the body is significant.

Ultimately, the choice is yours. The goal of this post is to provide the information you need to make an informed decision about your health. While some may tolerate moderate drinking, it’s essential to weigh the risks and make choices that align with your path to optimal well-being.

For more wellness-related content, stay connected with us and follow Cielo and Dr. Kenny on Instagram.

About the Author

Dr. Kenny Mittelstadt, DACM, DC, L.Ac., Dipl.OM.

Kenny Mittelstadt is a functional health practitioner and acupuncturist based in San Antonio, Texas. He is trained through the Institute for Functional Medicine and received both of his doctorate degrees with highest honors from Southern California University of Health Sciences. He focuses on empowering patients through wellness education and root-cause healing – transforming health through personalized, lab-based functional medicine programs!

Website: DrKennyMittelstadt.com

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